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Islam et al., 2024)

Oral supplementation is usually sufficient to treat deficiencies, with 1735 mg/kg per day of alpha-tocopherol

The difference in study results could be due to diet

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At the same time, AI-driven prediction models will be constructed by combining individualized microbiome characteristics (e.g., enterotyping, HLA polymorphisms, and baseline bacterial flora composition) to guide precise therapeutic strategies (Mkilima, 2025

However, the major drawback of this pioneer purification study was the employment of denaturing conditions, which triggered the improvement of the procedure by conducting binding under native conditions and elution with low concentrations of a competitor imidazole or EDTA (Janknecht et al., 1991, Westra et al., 2001)
