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Refining the diagnosis of mitochondrial HMG-CoA synthase deficiency

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The calculated rotation angle of the centres of mass of the D1-D2 region relative to LID/HID of 166 suggests a high degree of flexibility of these regions, at least in the absence of the CWB2-containing SLP H core, with minimal effects on the fold of each individual domain

Competing interests The authors have declared that there are no competing interests