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(Native, unmodified recombinant human IGF-1, sold as mecasermin/Increlex, is FDA-approved only for a narrow pediatric growth-failure indication and is chemically distinct from the LR3 analog.) In the US it is manufactured and sold almost exclusively as an unregulated "research chemical" labeled "not for human consumption," a labeling practice peptide vendors use to avoid marketing it as an unapproved drug

MVP Registration (page 1,449): Subgroups must register under an MVP but need not attest to specialty composition

Yoshikawa S, Kukimoto-Niino M, Parker L et al

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doi: 10.1016/S0197-4580(02)00069-6

Flow cytometry and sorting Flow cytometric analysis was performed using an LSRFortessa cytometer (BD Biosciences), cell sorting was performed using a FACSAria II sorter (BD Biosciences), and all data were analyzed with FlowJo software (Tree Star Inc.)