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t-Darpp activates IGF-1R/AKT signaling through heterodimerization with EGFR and HER2, promoting and stimulating glucose uptake, glycolysis and trastuzumab resistance in SK-BR-3 cells

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It increased surface GHRs in a biphasic manner, with a peak response at 10 nmol/L, and it modulated GH-induced Janus kinase-2 phosphorylation in parallel with the expression of surface GHRs [8]

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10.1111/j.1530-0277.2011.01616.x 94 MeinhardtM

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Insights on the evolution of trehalose biosynthesis

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Recognition and control of neutrophil extracellular trap formation by MICL

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DM1, mertansine/emtansine

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