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Here, we demonstrated that 2-DG interferes with proIGF-1Ea glycosylation preventing the formation of the normal, highly glycosylated proIGF-1Ea (~17 kDa) (Fig

Materials and methods Human monocyte-derived macrophages Approximately 40 mL of blood were collected via venipuncture from healthy (no known chronic or acute conditions

(2013) Impaired tethering and fusion of GLUT4 vesicles in insulin-resistant human adipose cells

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In mice subjected to sleep deprivation, it has been found that activation of microglia and astrocytes was accompanied by downregulation of 7 nicotinic acetylcholine receptor ( 7-nAChR), which is involved in the regulation of calcium-dependent events and cholinergic anti-inflammatory pathway