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The superoxide in mitochondria was examined using MitoSOX Red staining

Free fatty acids suppress glucose metabolism in peripheral tissues such as skeletal muscle

[DOI] [PubMed] [Google Scholar] 58.Sinha R, Sinha I, Calcagnotto A, Trushin N, Haley JS, Schell TD, Richie JP

To test the literature-based model, we systematically adjusted the various reaction rates by numerical optimization of the likelihood function to minimize the discrepancy between the time-course of the observed concentrations in the fluorescent reporter cell lines and the corresponding model predictions
