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We used human blood serum as a low-cost chemical library (Grndemann et al., 2005

[DOI] [PMC free article] [PubMed] [Google Scholar] 351.Tobias D.K., Chen M., E Manson J., Ludwig D.S., Willett W., Hu F.B

When a tumor or tumors form in the cells of the pituitary responsible for ACTH production (corticotropes) those tumorous out-of-control cells continuously release ACTH regardless of the cortisol level in your pets blood stream sort of like a faulty thermostat running your air conditioning system that never shuts off
