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doi:10.1126/sageke.2005.18.pe12

Notably, these neuroprotective effects were hydrogen-dependent, as silicon dioxide (SiO2) alone showed no comparable activity

10.3390/medicina56030128 83 SarkayaE.DoanS

Mechanistically, tolerance reflects rate matching between pollutant-driven production and antioxidant clearance, which can be expressed compactly as: with coupled redox pools Because NADPH supply, enzyme abundances, apoplastic ascorbate, and sulfur-assimilation capacity set the ceiling of redox throughput, genotypes with larger AsA-GSH pools, faster APX/CAT kinetics, and stronger fluxes tend to show superior resilience to SO 2 , NO x , and O 3 , while CO tolerance tracks with mitochondrial robustness and heme-protein turnover (Rahantaniaina et al., 2013