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Synthesis and characterization of JQ1-CA and Amide-CA can be found in Supplementary Note 1

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Any references to biological activity are provided strictly for research context and must not be interpreted as claims of safety, efficacy, or intended human use

Subsequently, to reduce the dosage intervals and enhance the bio availability, the drug releasing pattern of Glibenclamide was modified by forming mucoadhesive beads using sodium alignate and okra gum for drug entrapment, allowing sustained release for up to 8 h in the body [2, 78]

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