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It is worth noting that cellular senescence also plays important beneficial roles in physiological processes such as tissue development, wound healing, and tumor suppression (Suter et al., 2025)

Vitamin C mesotherapy versus diode laser for the esthetic management of physiologic gingival hyperpigmentation: A randomized clinical trial

Moreover, the simulations confirmed that the Cagri P37 had weaker interactions with the ECDs leading to greater uncoupling of the peptide C-terminus from the ECDs (Supplementary Movie 1, Supplementary Tables 4, 5), and parallel increases in the dynamics of the peptide as it engaged with the CTR TM bundle, including F23

Its essence lies in a complex pathological network that is driven by the overexpression of ER and PR-B

Maintain a Skincare Routine: Continue to follow a consistent skincare routine that includes gentle cleansing, moisturising, and sunscreen application

Proc Natl Acad Sci U S A (2010) 107(8):350510