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Although urinary BDNF may not be the ideal effect biomarker to address CNS alterations due to its secretion by kidneys and bladder tissues ( As shown in Figure 1, there are some adverse outcome pathways (AOPs) that could support and explain these results

A highly purified cysteine S -conjugate -lyase was obtained from E

doi: 10.1053/j.gastro.2019.06.048 91

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