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The plates were incubated aerobically, lid side up, in humidified plastic boxes at 37 C for 8 h, after which the diameter of the cloud of swimming cells was measured with a ruler

doi: 10.1021/acs.biochem.7b00199 41

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Likewise, polyphenols or omega-3 fatty acid combinations with chemotherapy are studied for pharmacodynamic synergy by means of endpoints such as tumour volume reduction, progression-free survival and amelioration of chemotherapy-induced toxicity along with quality-of-life enhancement, keeping a close watch for antagonistic interactions or organ-specific adverse effects (234)

Data from animal coronavirus vaccine development suggested that systemic cell-mediated or humoral immune reactions induced by parenteral management may not be enough to inhibit the virus invasion in the respiratory system (183)
