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Mutations of these genes lead to abnormally high incidence of cancer

Structure and mechanism of monoamine oxidase
I.HamidA.YousafR.HarisM.SaleemU.et al (2024)

Initiate treatment with the EPKINLY step-up dosage schedule to reduce the incidence and severity of CRS

A common polymorphism in HIBCH influences methylmalonic acid concentrations in blood independently of cobalaminAm J Hum Genet2016;98:869-82

Interestingly, other mechanisms besides protease-mediated degradation of the ECM can also limit fibrosis