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Current Opinion in Gastroenterology

JCI Insight 4:e123182

Stoev, 2013)

Although, like other SLC22 family members, SLC22A4 is capable of transporting multiple substrates, the transport efficiencies for other confirmed substrates are orders of magnitude lower than that of ergothioneine, and increasing evidence from independent laboratories demonstrates SLC22A4 is highly specific for ergothioneine (28,31,32)

Initial symptoms include fatigue, irritability, and appetite loss caused by impaired carnitine biosynthesis and fatty acid transport

Glutathione is a combination of the amino acids glutamine, glycine, and cystine