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This is, then, oxidized by cytosolic isocitrate dehydrogenase 1 (IDH1) to -ketoglutarate with the production of NADPH required for the detoxification from reactive oxygen species (ROS

ukawski M, Daek P, Borowik T, Fory A, Langner M, Witkiewicz W, Przybyo M (2020) New oral liposomal vitamin C formulation: properties and bioavailability

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However, the lens nucleus exhibits low protein turnover, rendering its proteins particularly susceptible to oxidative damage [17]

Mbaye B, Wasfy RM, Alou MT, Borentain P, Gerolami R, Dufour JC, Million M (2024) A catalog of ethanol-producing microbes in humans

This corresponded to a clinical improvement in 6 out of the 8 patients
