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In addition, a meta-analysis of four clinical trials demonstrated that after three to 6 months of metformin use it significantly reduced vitamin B 12 levels [85]
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Is It Safe to Take Vitamin B12
It can be used for neuralgia, rheumatism of the soft tissues, arthritic conditions, carpal tunnel syndrome, sciatica, herniated/bulging disc pain
These effects all contribute to the process of tendon healing
doi: 10.1016/j.ejphar.2004.01.015
These improvements occurred even in subjects who lost only modest amounts of weight, suggesting metabolic benefits beyond simple weight reduction
