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J., Greig I., Helfrich M

Animal studies show that reduced pineal gland production of melatonin causes low bone mass and that a deficiency of the MT2 melatonin receptor also causes low bone mass
Many of the conducted trials have not been a double-blind design, which reduces the risk of bias

Yang J, Cha L, Wang Y, Zhang Q, Tang X, Shao J, et al
Seim H., Loster H., Kleber H

The comparison breaks down like this