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Bipolar disorder: A landmark RCT (n=75) found that NAC (1,000 mg twice daily for 24 weeks) produced a significant improvement in depression scores (Montgomery-Asberg Depression Rating Scale) in bipolar disorder as an adjunct to usual treatment (Berk et al., Biol Psychiatry, 2008) [74]

Parameter Group Cisplatin control Cisplatin + KND Cisplatin + peptide (III) Cisplatin + peptide (IV) The liver mass, g 10.8087 0.4824a12.8795 0.6407b11.2675 0.4992 11.2326 0.7664 10.5268 0.4603a The kidney mass, g 4.9563 0.2469a3.3028 0.1387b4.1516 0.2962a, b 4.0257 0.3715b4.0558 0.1377b RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY Vol

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Qiao Z, Li Y, Li S, Liu S, Cheng Y

- Vitamin E is an exogenous antioxidant that forms a non-enzymatic antioxidant system with glutathione and vitamin C