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As the main source of protein for the Minamata population was fish, they were consequently exposed to high levels of MeHg +

Further, elevated miR18a expression and AFP abundance correlate with diminished GCLC expression and GSH abundance, respectively, in human liver cancer

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The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity

Further research published in the Journal of Allergy and Clinical Immunology indicates that glutathione depletion may be a key factor in the increased inflammatory response seen in children who frequently use acetaminophen

PloS One 9 , e103282