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2 Garvey WT, Blher M, Osorto Contreras CK, et al

Prolonged activation of microglia and astrocytes, key players in neuroinflammation, can precipitate neurodegenerative diseases (2628)

10.1016/j.abb.2008.06.011 38 FormentiniL.Sanchez-AragoM.Sanchez-CenizoL.CuezvaJ

110 MiR-122 is predominantly generated in the liver and constantly released into the circulation 111 and has been shown to be significantly elevated in patients with acute HF

Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats

Another study revealed, using CARS2 heterozygous knockout mice, that CARS2 plays an anti-inflammatory role under various inflammatory conditions [79]