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Phase 1b study of safety, tolerability and efficacy of R1507, a monoclonal antibody to IGF-1R in combination with multiple standard oncology regimens in patients with advanced solid malignancies

Doessing, S., et al

J Plant Physiol 164:553561

Moreover, the analysis of some outcomes, such as LLT and CFS, included a relatively small number of studies, potentially compromising the reliability of the findings and increasing the risk of publication bias

Although it is well established that a drop in plasma glucose drives an elevation in glucagon secretion, the precise mechanisms that control this response of -cells to hypoglycemia remain incompletely understood

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