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However, chalcones are generally poorly soluble in water or practically insoluble, which significantly limits their biological utilization and application [21,28,83]

Perinelli et al., 2018)

Combined treatment with FHD-286 and other epigenetic drugs, such as decitabine, BET inhibitors, and menin inhibitors, has demonstrated synergistic effects in reducing AML burden without significant toxicity

Acute and delayed infusion reactions which didn't respond to premedication occurred in 2 of the 15

[Positive effects of DHEA therapy on insulin resistance and lipids in men with angiographically verified coronary heart disease--preliminary study]

Knopman et al., 2021)
