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6 Only 3 uncontrolled pilot studies with a combined sample size of 30 participants have been reported

Over weeks, it's obvious

Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this article

The choice of agent is influenced by individual disease activity, patient profile, and safety considerations [145]

B12 shots are designed to boost your energy and support metabolism, but they don't directly target fat cells

There is also recent data which suggest that genetic alterations of the receptor by which B12 is transported into nerve tissue and the brain, may lead to a lower B12 uptake