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doi:10.1038/s42255-023-00917-5

Had to take more than the recommended dosage

Reducing the risk of metabolic diseases: Inhibiting NNMT may counteract the adverse metabolic changes associated with obesity, such as fatty liver disease

It operates by mimicking the natural action of HGH on fat metabolism but without the muscle growth, water retention, or potential side effects associated with HGH use

Unlike anabolic steroids, which directly impact protein synthesis and testosterone levels, IGF-1 influences cell repair and regeneration, as well as fat metabolism, which makes it a unique compound for performance enhancement

Potential benefits of using GLP-1 receptor agonists after gastric sleeve surgery include: Enhanced weight loss : Observational studies suggest post-bariatric patients using GLP-1 receptor agonists may achieve additional weight reduction, typically around 510% of body weight, though individual responses vary considerably Improved glycaemic control : Particularly beneficial for patients with type 2 diabetes or prediabetes, as GLP-1 agonists enhance insulin secretion and reduce blood glucose levels Reduced appetite : These medications can help patients who struggle with persistent hunger despite surgical intervention Cardiovascular benefits : Semaglutide has demonstrated cardiovascular risk reduction in people with established cardiovascular disease, which may benefit eligible post-bariatric patients with this specific risk profile Maintenance of weight loss : May help prevent weight regain during the critical maintenance phase Potential risks and considerations include: Gastrointestinal side effects : Nausea, vomiting, diarrhoea, and constipation are common, particularly during dose escalation