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Unprecedented strides have been made in studying ferroptosis induction by botanical drugs and isolated metabolites in lung cancer cells (Chen et al., 2020

Natural compounds can modulate immune surveillance by enhancing NK cell activity, promoting dendritic cell maturation, and shifting macrophage polarization toward a tumorsuppressive M1 phenotype (cited [83, 84, 85, 146, 154])

Consequently, it has been proposed that exploring the master regulator of antioxidant responses Nuclear factor erythroid 2-related factor 2 (Nrf-2), may provide novel biomarkers for determining the sensitization potential of several chemicals (Natsch and Emter, 2008

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[DOI] [PubMed] [Google Scholar] 75.Babu G., Bawari M., Ali M
