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Physical Therapy for Functional Dystonia Evidence supporting PT as an integral component of a multimodal treatment approach for functional neurological disorders has amassed over the last half century (185, 190194)

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In preclinical work it up- and down-regulates a large number of genes tied to matrix production, remodeling, and antioxidant defense, and it ferries copper a cofactor for lysyl oxidase and superoxide dismutase into tissue

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However, less commonly, keratinized mucosa may also be involved, such as the dorsum (top surface) of the tongue or the gingiva (gums)