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To maintain redox balance and avoid reductive stress, NAD must be regenerated in cells with high glycolysis flux

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Investigating icariin and icaritin anti-cancer effects through drug delivery system The utilization of various delivery platforms, including phospholipid complexes, cyclodextrin complexes, micellar formations, nano-carriers, and solid materials, significantly enhance the bioavailability of icariin and icaritin, exhibiting remarkable potential in the treatment of breast, lung and gastric cancers [776,777,778]

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In: Blanco A, Blanco G, editors