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Description
Formal online e-learning was the preferred education mode (67%)

The first step of SSP is catalyzed by phosphoglycerate dehydrogenase (PHGDH), which converts 3-phosphoglycerate (3-PG), derived from glucose, into 3-phosphohydroxypyruvate (3-PHP) with concomitant reduction of NAD + to NADH ( D -2HG within the cellular milieu ( PHGDH impairment has broad metabolic consequences, affecting serine availability, the TCA cycle anaplerosis, redox balance, energy metabolism, nutrient sensing, and cell signaling ( D -isomer metabolites

10 , e101848 (2020)

Mitochondria need NAD+ to function

This page summarises published research for educational purposes

Cravedi P, Remuzzi G
