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The immobilization of the enzyme arises subsequent in the development of Cross-Linked (soluble) Enzyme (CLE), Cross-Linked Enzyme Crystals (CLEC), Crosslinked Enzyme Aggregates (CLEA), and Cross-Linked Spraydrying Enzyme (CSDE) when these enzymes are placed in a medium containing a cross-linking agent [175, 176]

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Conclusively, these results suggest that ALC is capable to attenuate kainate-induced SE which is somewhat mediated through its lowering of oxidative stress, neuroinflammation, and pyroptosis that are related to its neuroprotective effect

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