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NAC also increased GSH levels, protected against A-induced protein and lipid peroxidation, and decreased acetylcholine levels and choline acetyltransferase (ChAT) activity [47]
Depletion of the macrophages partially reversed this mechanical hypersensitivity and reduced the expression of the proinflammatory cytokine TNF-, as did the injection of the MCP-1 (methyl-accepting chemotaxis proteins -1, whose receptor is CCR2) neutralizing antibody
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