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[DOI] [PMC free article] [PubMed] [Google Scholar] 876.Dharmajaya R., Sari D.K

Emerging evidence suggests that TMAO may play a role in the pathogenesis of various kidney diseases, including acute kidney injury and chronic kidney disease

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probiotic treatment significantly suppressed these neuroinflammatory pathways ( Moreover, SCFAs and tryptophan metabolites, as key mediators of bidirectional gut-brain communication, play essential roles in maintaining intestinal barrier integrity, modulating immune function, and transmitting signals via the vagus nerve (Pan et al., 2025)

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