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Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation

Institutional review board statement This study did not involve humans or animals

Brief Summary Abundant preclinical experiments have been performed in both cancer cells and tumor xenograft models, and they have confirmed that drugs and antibodies targeting IGF-1/IGF-1R signaling have antitumor growth effects

High-cysteine foods are mainly those from the animal kingdom with beef, chicken, pork, and turkey containing some of the highest amounts