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The researchers looked at the bacteria's gene expression, hoping to figure out why Propionibacterium acnes , which is the most common skin microbe, causes pimples in some people but not in others

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[24] References (Trusted Sources) FDA Guide to Inspections of Lyophilization of Parenterals (7/93): definition of lyophilization (freeze-drying) and process overview

IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes

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Human tolerability data comes from Phase I and II clinical investigations in obese adult volunteers