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Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors

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Oxidative stress and mitochondrial dysfunction are considered central features of neurodegenerative diseases [26], and the long-term use of KD may positively affect mitochondrial function through several mechanisms

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While detox symptoms like mild fatigue or a temporary breakout usually resolve within a few days, some side effects require a different approach

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Each data set represents n = 3 biological replicates

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Enteric glial cells counteract Clostridium difficile toxin B through a NADPH oxidase/ROS/JNK/caspase-3 axis, without involving mitochondrial pathways

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