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(August 2001)

5 PHARMACOLOGICAL PROPERTIES 5.1 Pharmacodynamic properties A.22.2 Vitamins: Others Vitamins B1, B6 and B12 act as coenzymes and accordingly constitute substances essential for metabolism

For this reason, intravenous colchicine is very rarely used today

[28] Although not relevant at clinical dosages, bromantane has been found to produce anticholinergic effects, including both antimuscarinic and antinicotinic actions, at very high doses in animals, and these effects are responsible for its toxicity (that is, LD 50 ) in animals

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