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Description
Severe OxS with elevated blood levels of high sensitivity-C-reactive protein (hs-CRP) is a hallmark of hyper-inflammatory state in COVID-19 and PASC 290,553,615
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Because the major site of action for metformin is the liver its use can be contraindicated in patients with liver dysfunction
Finally, we highlight major limitations in the current evidencesuch as heterogeneous dosing regimens, the scarcity of long-term clinical data, and insufficient mechanistic validation under MASLD conditionsand propose directions for future translational research
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If meaningful benefit is observed (e.g
