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B12 is water-soluble, so your body will excrete what it doesn't need

Expression levels of MTRR, the gene responsible for reducing B12 to its active form for use by MS, are increased in ovarian carcinoma and targeting MTRR using RNA interference has been shown to inhibit growth and cisplatin resistance in both in vitro and in vivo models, making it a potential target for therapy [178]

PMID: 42041131 Adv Sci (Weinh) Gene Therapy for Inflammatory Cascade in Intrauterine Injury with Engineered Extracellular Vesicles Hybrid Snail Mucus-enhanced Adhesive Hydrogels

In addition, the GHS has been reported to have the following potential benefits in adults when given orally [5, 7]: Increased muscle mass without increases in adiposity Reduction of cholesterol levels Improved sleep It's important to note that MK-677 is still under investigation and has not received FDA approval for any indication