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Alzheimer's disease: treatment challenges for the future

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[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Chan K, Han XD, Kan YW

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Huh7 and H1299 cells (1 10 4 per well) were sequentially treated with 1.5 M oligomycin, 1 M carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone and 1 M rotenoneantimycin A (both 0.5 M) (all from Sigma)

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Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

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The signal peptide is removed intracellularly to generate proLOX, which contains the propeptide and the catalytic domain

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Loss of TDP-43 in male germ cells causes meiotic failure and impairs fertility in mice

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