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Alzheimer's disease: treatment challenges for the future

[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Chan K, Han XD, Kan YW

Huh7 and H1299 cells (1 10 4 per well) were sequentially treated with 1.5 M oligomycin, 1 M carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone and 1 M rotenoneantimycin A (both 0.5 M) (all from Sigma)

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

The signal peptide is removed intracellularly to generate proLOX, which contains the propeptide and the catalytic domain
Loss of TDP-43 in male germ cells causes meiotic failure and impairs fertility in mice