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Yap and Winckler, 2022

The adrenal glands also undergo changes as the body ages

Cunningham-Rundles, S

As an example, GSTs protect cellular DNA against oxidative damage that can lead to an increase of DNA mutations or induce DNA damage promoting carcinogenesis 9

Thus, the monosaccharides fructose, galactose, and ribose join upstream in the glycolytic pathway of cancer cells that express suitable GLUTs, kinases, or other enzymes favoring uridine catabolism

The elimination strategy targeting senescent cells thus represents a promising area of research in the context of various pathologies, including cancer, cardiovascular, and neurodegenerative diseases, by targeting the very biological foundation of aging