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31 Survotutide was studied in once and twice weekly administration by subcutaneous injection in a phase II trial, and was shown to significantly reduce HbA1c compared to placebo (Table 1)

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Proteins 76 , 852860 (2009)

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In parallel, generative models such as RoseTTAFold and RFdiffusion [51, 52] have enabled de novo design of antibody scaffolds and binding interfaces