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The endothelial cells, smooth muscle cells, and immune cells of the vessel wall can form a complex inflammatory network by secreting inflammatory mediators, which jointly promote the sustained increase of blood pressure (58, 59)

Everything else comes from animal models

Phytother Res 31:340344 Machova Urdzikova L, Cimermanova V, Karova K, Dominguez J, Stepankova K, Petrovicova M, Havelikova K, Gandhi CD, Jhanwar-Uniyal M, Jendelova P (2023) The role of green tea catechin epigallocatechin gallate (EGCG) and mammalian target of rapamycin (mTOR) inhibitor PP242 (Torkinib) in the treatment of spinal cord injury

CS contains thousands of reactive oxidants and free radicals, directly imposing oxidative stress on pulmonary cells

Abstract While aging is typically synonymous with the lifespan of an individual, the healthspan, or the total number of years an individual remains healthy and disease-free, is not necessarily related